Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 5/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5216357 | 0.96 | TP53 (0.41) | RARBMAPTMEN1ALDH1A1RARA | |
| SCHEMBL5219112 | 0.93 | TP53 (0.39) | MAPTMEN1ALDH1A1KMT2ATP53 | |
| SCHEMBL5125044 | 0.92 | TP53 (0.40) | MAPTTP53SCN9A | |
| SCHEMBL5118191 | 0.91 | TP53 (0.39) | RARBMAPTALDH1A1RARATP53 | |
| SCHEMBL5111306 | 0.91 | TP53 (0.39) | RARBMAPTALDH1A1RARATP53 | |
| SCHEMBL5126197 | 0.90 | TP53 (0.39) | RARBMAPTALDH1A1RARATP53 | |
| SCHEMBL5118444 | 0.88 | TP53 (0.42) | MAPTMEN1ALDH1A1KMT2ATP53 | |
| SCHEMBL5113535 | 0.86 | TP53 (0.38) | RARBMAPTALDH1A1RARATP53 | |
| SCHEMBL5124414 | 0.85 | TP53 (0.39) | RARBMAPTALDH1A1RARATP53 | |
| SCHEMBL5117738 | 0.83 | TP53 (0.37) | RARBMAPTMEN1ALDH1A1RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828124-A1 | BIAROMATIC COMPOUNDS THAT MODULATE PPAR TYPE RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development (FR) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006063863-A1 | BIAROMATIC COMPOUNDS THAT MODULATE PPAR TYPE RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2006-06-22 | — | — | WO | disclosed |