SCHEMBL5256113

SCHEMBL5256113

COc1oc(-c2cccs2)nc1CCOc1ccc(CN(CC(=O)O)S(=O)(=O)N(c2ccccc2)S(C)(=O)=O)cc1

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 19/20 0.46
PPARG P37231 18/20 0.46
PPARD Q03181 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5441048 0.92 PPARA (0.46) PPARAPPARGPPARD
SCHEMBL5262656 0.84 PPARA (0.48) PPARAPPARGPPARD
SCHEMBL5225422 0.82 PPARG (0.57) PPARAPPARGPPARD
SCHEMBL5225327 0.80 PPARG (0.59) PPARAPPARGPPARD
SCHEMBL5225901 0.80 PPARA (0.41) PPARAPPARGPPARD
SCHEMBL5269968 0.79 PPARA (0.41) PPARAPPARGPPARD
SCHEMBL5226283 0.79 PPARG (0.53) PPARAPPARGPPARD
SCHEMBL5231601 0.77 PPARA (0.55) PPARAPPARGPPARD
SCHEMBL5226980 0.75 PPARG (0.57) PPARAPPARGPPARD
SCHEMBL5224731 0.75 PPARA (0.58) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1778654-A1 SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME Crystalgenomics, Inc. (KR) 2007-05-02 EP disclosed
WO-2006006832-A1 SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME CRYSTALGENOMICS, INC. (KR) 2006-01-19 WO disclosed