Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 20/20 | 0.62 |
| ▸ | ICAM1 | P05362 | 20/20 | 0.62 |
| ▸ | ITGAL | P20701 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5449287 | 0.86 | ITGB2 (0.69) | ITGB2ICAM1ITGAL | |
| SCHEMBL7646849 | 0.83 | ITGB2 (0.74) | ITGB2ICAM1ITGAL | |
| SCHEMBL5256346 | 0.81 | ITGB2 (0.60) | ITGB2ICAM1ITGAL | |
| SCHEMBL5303915 | 0.80 | ITGB2 (0.65) | ITGB2ICAM1ITGAL | |
| SCHEMBL5196362 | 0.79 | ITGB2 (0.72) | ITGB2ICAM1ITGAL | |
| SCHEMBL5195705 | 0.79 | ITGB2 (0.80) | ITGB2ICAM1ITGAL | |
| SCHEMBL4895830 | 0.78 | ITGB2 (0.71) | ITGB2ICAM1ITGAL | |
| SCHEMBL7642426 | 0.78 | ITGB2 (0.71) | ITGB2ICAM1ITGAL | |
| SCHEMBL14066354 | 0.76 | ITGB2 (1.00) | ITGB2ICAM1ITGAL | |
| SCHEMBL4893722 | 0.76 | ITGB2 (1.00) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740565-A2 | ARYLPHENYLAMINO-, ARYLPHENYLAMIDE-, AND ARYLPHENYLETHER-SUFIDE DERIVATIVES | ICOS Corporation (US) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005105770-A2 | ARYLPHENYLAMINO-, ARYLPHENYLAMIDE-, AND ARYLPHENYLETHER-SULFIDE DERIVATIVES | ICOS CORPORATION (US) | 2005-11-10 | — | — | WO | disclosed |