Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4941437 | 0.92 | IKBKB (0.57) | IKBKB | |
| SCHEMBL5253960 | 0.90 | IKBKB (0.72) | IKBKB | |
| SCHEMBL4938349 | 0.85 | IKBKB (0.63) | IKBKB | |
| SCHEMBL5252161 | 0.85 | IKBKB (0.57) | IKBKB | |
| SCHEMBL4946395 | 0.84 | IKBKB (0.68) | IKBKB | |
| SCHEMBL4613934 | 0.84 | IKBKB (0.81) | IKBKB | |
| SCHEMBL4947170 | 0.84 | IKBKB (0.71) | IKBKB | |
| SCHEMBL27583738 | 0.81 | IKBKB (0.65) | IKBKB | |
| SCHEMBL7170770 | 0.80 | IKBKB (0.54) | IKBKB | |
| SCHEMBL14046403 | 0.77 | IKBKB (0.80) | IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326856-B1 | PYRIDINE DERIVATIVES WITH IKB-KINASE (IKK-BETA) INHIBITING ACTIVITY | BAYER HEALTHCARE AG (DE) | 2007-12-19 | — | — | EP | claimed |