⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19813735 | 0.86 | — | — | |
| SCHEMBL15064873 | 0.79 | — | — | |
| SCHEMBL15535793 | 0.74 | — | — | |
| SCHEMBL18405575 | 0.72 | — | — | |
| SCHEMBL7858274 | 0.72 | — | — | |
| SCHEMBL15854757 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL6796156 | 0.69 | — | — | |
| SCHEMBL14354430 | 0.69 | — | — | |
| SCHEMBL3300416 | 0.69 | — | — | |
| SCHEMBL3754802 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208962-A1 | MICROBIOCIDAL QUINOLINE/QUINOXALINE BENZOTHIAZINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-27 | — | — | US | disclosed |
| EP-4312556-A1 | MICROBIOCIDAL QUINOLINE/QUINOXALINE BENZOTHIAZINE DERIVATIVES | Syngenta Crop Protection AG (CH) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022207665-A1 | MICROBIOCIDAL QUINOLINE/QUINOXALINE BENZOTHIAZINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-10-06 | — | — | WO | disclosed |
| EP-1517895-B1 | 8-(BIARYL) QUINOLINE PDE4 INHIBITORS | MERCK FROSST CANADA LTD (CA) | 2007-03-14 | — | — | EP | disclosed |
| US-7153968-B2 | 8-(biaryl)quinoline PDE4 inhibitors | MERCK FROSST CANADA, LTD. (CA) | 2006-12-26 | — | — | US | disclosed |
| US-20050234238-A1 | 8-(Biaryl)quinoline pde4 inhibitors | MERCK FROSST CANADA LTD. (CA) | 2005-10-20 | — | — | US | disclosed |
| EP-1517895-A1 | 8-(BIARYL) QUINOLINE PDE4 INHIBITORS | MERCK FROSST CANADA INC. (CA) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000814-A1 | 8-(BIARYL) QUINOLINE PDE4 INHIBITORS | MERCK FROSST CANADA & CO. (CA) | 2003-12-31 | — | — | WO | disclosed |