Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 11/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4337387 | 0.92 | BDKRB1 (0.34) | BDKRB1 | |
| SCHEMBL4336016 | 0.91 | BDKRB1 (0.38) | BDKRB1 | |
| SCHEMBL4338055 | 0.91 | BDKRB1 (0.37) | BDKRB1 | |
| SCHEMBL4342940 | 0.90 | BDKRB1 (0.38) | BDKRB1 | |
| SCHEMBL4342342 | 0.90 | BDKRB1 (0.37) | BDKRB1 | |
| SCHEMBL4344359 | 0.90 | BDKRB1 (0.37) | BDKRB1 | |
| SCHEMBL4342031 | 0.90 | BDKRB1 (0.37) | BDKRB1 | |
| SCHEMBL4349175 | 0.89 | BDKRB1 (0.39) | BDKRB1 | |
| SCHEMBL4335980 | 0.89 | BDKRB1 (0.36) | BDKRB1 | |
| SCHEMBL4341974 | 0.88 | BDKRB1 (0.37) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817306-A1 | TRIAZOLES AND THEIR USE AS BRADYKININ B1 RECEPTOR ANTAGONISTS | Amgen, Inc (US) | 2007-08-15 | — | — | EP | claimed |
| WO-2006044355-A1 | TRIAZOLES AND THEIR USE AS BRADYKININ B1 RECEPTOR ANTAGONISTS | AMGEN INC. (US) | 2006-04-27 | — | — | WO | claimed |
| EP-1817306-A1 | TRIAZOLES AND THEIR USE AS BRADYKININ B1 RECEPTOR ANTAGONISTS | Amgen, Inc (US) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006044355-A1 | TRIAZOLES AND THEIR USE AS BRADYKININ B1 RECEPTOR ANTAGONISTS | AMGEN INC. (US) | 2006-04-27 | — | — | WO | disclosed |