SCHEMBL5260074

SCHEMBL5260074

CC(C(=O)N(C)C)N1CCC(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5226891 1.00 F10 (1.00) F10
SCHEMBL5230169 0.93 F10 (1.00) F10
SCHEMBL5226588 0.91 F10 (1.00) F10
SCHEMBL5225938 0.90 F10 (0.82) F10
SCHEMBL5227804 0.90 F10 (0.82) F10
SCHEMBL5230134 0.90 F10 (1.00) F10
SCHEMBL5223662 0.89 F10 (0.84) F10
SCHEMBL5224114 0.89 F10 (0.80) F10
SCHEMBL4479070 0.89 F10 (0.82) F10
SCHEMBL5144940 0.89 F10 (0.82) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1444201-B1 2-(3-SULFONYLAMINO-2-OXOPYRROLIDIN-1-YL)PROPANAMIDES AS FACTOR XA INHIBITORS GLAXO GROUP LTD (GB) 2007-09-12 EP disclosed