Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 3/20 | 0.47 |
| ▸ | MGAM | O43451 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | SI | P14410 | 5/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.46 |
| ▸ | GUSB | P08236 | 4/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5259743 | 0.87 | SNCA (0.47) | SNCAMGAMGAASIMGAM2 | |
| SCHEMBL5257331 | 0.81 | F7 (0.45) | SNCAF7F3NR4A2 | |
| SCHEMBL5259028 | 0.76 | SRC (0.51) | MGAMGAASIMGAM2GUSB | |
| SCHEMBL2980996 | 0.73 | F7 (0.63) | SNCAF7F3POLBDUSP3 | |
| SCHEMBL949420 | 0.71 | POLB (0.56) | MGAMGAASIMGAM2GUSB | |
| SCHEMBL7234600 | 0.70 | F7 (0.58) | F7F3NR4A2MTNR1AMTNR1B | |
| SCHEMBL28596805 | 0.69 | F7 (0.54) | F7F3NR4A2TSHRMTNR1A | |
| SCHEMBL14631392 | 0.68 | F7 (0.49) | SNCAMGAMGAASIMGAM2 | |
| SCHEMBL5259745 | 0.68 | IDO1 (0.49) | MGAMGAASIMGAM2SLC6A4 | |
| SCHEMBL31567623 | 0.68 | HTR2A (0.55) | GUSBF7F3NR4A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1261585-B1 | SUBSTITUTED INDOLE MANNICH BASES | GRUENENTHAL GMBH (DE) | 2007-09-26 | — | — | EP | claimed |