SCHEMBL526016

SCHEMBL526016

CC(C)CC(CC=O)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 2/20 0.52
SLC1A2 P43004 2/20 0.52
CPA1 P15085 1/20 0.48
LAP3 P28838 2/20 0.43
RNPEP Q9H4A4 1/20 0.43
ANPEP P15144 1/20 0.43
SLC7A5 Q01650 1/20 0.43
MME P08473 3/20 0.42
GRIK1 P39086 8/20 0.41
GRIK2 Q13002 8/20 0.41
SLC1A1 P43005 1/20 0.39
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16649193 0.84 GRIK1 (0.40) SLC1A3SLC1A2CPA1RNPEPSLC7A5
SCHEMBL8389926 0.84 FOLH1 (0.41) MMEGRIK1GRIK2
SCHEMBL27799807 0.81 GRIK1 (0.38) SLC1A3SLC1A2CPA1MMEGRIK1
SCHEMBL4795102 0.80 GRIK1 (0.62) SLC1A3SLC1A2CPA1LAP3RNPEP
SCHEMBL1885655 0.80 GRIK1 (0.62) SLC1A3SLC1A2CPA1LAP3RNPEP
SCHEMBL7305997 0.80 GRIK1 (0.62) SLC1A3SLC1A2CPA1LAP3RNPEP
SCHEMBL3572242 0.80 SLC1A3 (0.41) SLC1A3SLC1A2CPA1LAP3RNPEP
SCHEMBL13675503 0.80 CHRM1 (0.39) SLC1A3SLC1A2CPA1GRIK1GRIK2
SCHEMBL276879 0.80 SLC1A3 (0.73) SLC1A3SLC1A2CPA1LAP3RNPEP
SCHEMBL10136584 0.78 GRIK1 (0.67) SLC1A3SLC1A2CPA1LAP3RNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2598504-A1 PROCESS FOR THE PREPARATION OF DIMIRACETAM Neurotune AG (CH) 2013-06-05 EP disclosed
WO-2012013640-A1 PROCESS FOR THE PREPARATION OF DIMIRACETAM NEUROTUNE AG (CH) 2012-02-02 WO disclosed
US-5130319-A Cognition activators for memory disorders I.S.F. SOCIETA PER AZIONI (IT) 1992-07-14 US disclosed
US-4472380-A CARBOXYALKYL DIPEPTIDE DERIVATIVES MERCK & CO., INC. (US) 1984-09-18 US disclosed
US-4374829-A Aminoacid derivatives as antihypertensives MERCK & CO., INC. (US) 1983-02-22 US disclosed
EP-0012401-A1 Carboxyalkyl dipeptide derivatives, process for preparing them and pharmaceutical composition containing them MERCK & CO. INC. (US) 1980-06-25 EP disclosed