SCHEMBL5260306

SCHEMBL5260306

COc1ccc2ncc(F)c(C(O)CN3CCOC(C(NC(=O)O)C(C)(C)C)C3)c2n1

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 4/20 0.51
SLC2A1 P11166 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5426672 0.81 KCNH2 (0.51) KCNH2SLC2A1
SCHEMBL5429187 0.81 KCNH2 (0.51) KCNH2SLC2A1
SCHEMBL5434350 0.81 KCNH2 (0.51) KCNH2SLC2A1
SCHEMBL14357560 0.81 KCNH2 (0.50) KCNH2
SCHEMBL14357559 0.81 KCNH2 (0.50) KCNH2
SCHEMBL5257438 0.80 KCNH2 (0.55) KCNH2
SCHEMBL5259412 0.80 KCNH2 (0.55) KCNH2
SCHEMBL5261023 0.78 KCNH2 (0.48) KCNH2SLC2A1
SCHEMBL5746937 0.74 KCNH2 (0.56) KCNH2SLC2A1
SCHEMBL14386272 0.74 KCNH2 (0.46) KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1773831-A1 ANTIBACTERIAL AGENTS GLAXO GROUP LIMITED (GB) 2007-04-18 EP disclosed
WO-2006014580-A1 ANTIBACTERIAL AGENTS GLAXO GROUP LIMITED (GB) 2006-02-09 WO disclosed