Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 2/20 | 0.35 |
| ▸ | NPY1R | P25929 | 9/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2006305 | 0.82 | HRH3 (0.49) | — | |
| SCHEMBL5264808 | 0.81 | ACP1 (0.41) | ACP1NPY1RGHSRMAP2K1 | |
| SCHEMBL2008384 | 0.73 | HRH3 (0.52) | — | |
| SCHEMBL5258954 | 0.70 | KCNH2 (0.52) | ACP1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL4462952 | 0.67 | HRH3 (0.60) | — | |
| SCHEMBL2006331 | 0.66 | HRH3 (0.53) | — | |
| SCHEMBL4471067 | 0.66 | HRH3 (0.65) | — | |
| SCHEMBL5258160 | 0.66 | KCNH2 (0.51) | NPY1RADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL2005785 | 0.66 | HRH3 (0.59) | — | |
| SCHEMBL2001416 | 0.66 | HRH3 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1757594-A1 | QUINAZOLINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-02-28 | — | — | EP | claimed |