SCHEMBL526076

SCHEMBL526076

CSCCC(NCc1ccccc1)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.58
LTA4H P09960 1/20 0.53
GAA P10253 1/20 0.52
ALDH1A1 P00352 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
LMNA P02545 1/20 0.49
PKM P14618 1/20 0.49
FNTA P49354 4/20 0.48
FNTB P49356 4/20 0.48
PDCD1 Q15116 1/20 0.48
CD274 Q9NZQ7 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL526077 1.00 ANPEP (0.58) ANPEPLTA4HGAAALDH1A1NPSR1
Hydrochloric Acid SCHEMBL29199142 0.98 ANPEP (0.56) ANPEPLTA4HGAAALDH1A1NPSR1
Hydrochloric Acid SCHEMBL30137695 0.98 ANPEP (0.56) ANPEPLTA4HGAAALDH1A1NPSR1
Acrylic Acid SCHEMBL1876772 0.92 ANPEP (0.51) ANPEPLTA4HGAAALDH1A1NPSR1
SCHEMBL7265651 0.88 ANPEP (0.55) ANPEPLTA4HGAA
SCHEMBL3649405 0.87 HTT (0.55) ANPEPGAAFNTAFNTB
SCHEMBL3649406 0.87 HTT (0.55) ANPEPGAAFNTAFNTB
Acrylic Acid SCHEMBL17975813 0.86 GAA (0.46) ANPEPLTA4HGAAALDH1A1NPSR1
SCHEMBL30402768 0.86 FNTA (0.56) ANPEPLTA4HALDH1A1FNTAFNTB
Hydrochloric Acid SCHEMBL1886525 0.85 HTT (0.54) ANPEPGAAFNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190134196-A1 ETAR ANTIBODY, AND PHARMACEUTICAL COMPOSITIONS AND USE THEREOF GMAX BIOPHARM LLC (CN) 2019-05-09 US claimed
EP-3476864-A1 ETAR ANTIBODY, PHARMACEUTICAL COMPOSITION AND USE THEREOF Gmax Biopharm LLC (CN) 2019-05-01 EP claimed
US-12594334-B2 ETAR antibody, and pharmaceutical compositions and use thereof GMAX BIOPHARM LLC. (CN) 2026-04-07 US disclosed
CN-119954890-A Optically pure small peptide chemiluminescent probe and application thereof in mycobacterium tuberculosis recognition 广东工业大学 2025-05-09 CN disclosed
US-20230346932-A1 ETAR ANTIBODY, AND PHARMACEUTICAL COMPOSITIONS AND USE THEREOF GMAX BIOPHARM LLC. (CN) 2023-11-02 US disclosed
US-20190134196-A1 ETAR ANTIBODY, AND PHARMACEUTICAL COMPOSITIONS AND USE THEREOF GMAX BIOPHARM LLC (CN) 2019-05-09 US disclosed
EP-3476864-A1 ETAR ANTIBODY, PHARMACEUTICAL COMPOSITION AND USE THEREOF Gmax Biopharm LLC (CN) 2019-05-01 EP disclosed
EP-2598160-A2 STABILIZATION OF FSH Ferring BV (NL) 2013-06-05 EP disclosed
CN-101597321-B LHRH antagonist with long-acting low-histamine release side effect INST PHARM & TOXICOLOGY AMMS 2013-04-24 CN disclosed
WO-2012013742-A2 STABILIZATION OF FSH FERRING B.V. (NL) 2012-02-02 WO disclosed
US-20110105567-A1 Pyrrole Compounds Having Sphingosine-1-Phosphate Receptor Agonist Or Antagonist Biological Activity ALLERGAN, INC. (US) 2011-05-05 US disclosed
EP-2185506-A1 PYRROLE COMPOUNDS HAVING SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST OR ANTAGONIST BIOLOGICAL ACTIVITY Allergan, Inc. (US) 2010-05-19 EP disclosed
CN-101597321-A The lhrh antagonist of long-acting low-histamine release side effect INST PHARM & TOXICOLOGY AMMS (CN) 2009-12-09 CN disclosed
WO-2009026407-A1 PYRROLE COMPOUNDS HAVING SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST OR ANTAGONIST BIOLOGICAL ACTIVITY ALLERGAN, INC. (US) 2009-02-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12594334-B2 ETAR antibody, and pharmaceutical compositions and use thereof EDNRA, FLT1, VEGFA ANPEP 793/4885LTA4H 3585/4885GAA 4809/4885
US-20110105567-A1 Pyrrole Compounds Having Sphingosine-1-Phosphate Receptor Agonist Or Antagonist Biological Activity S1PR1, S1PR2, S1PR3 ANPEP 1641/4885LTA4H 557/4885GAA 1804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.