⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14997057 | 0.70 | — | — | |
| SCHEMBL27246 | 0.70 | — | — | |
| SCHEMBL6230212 | 0.67 | CETP (0.56) | — | |
| SCHEMBL459896 | 0.67 | CETP (0.56) | — | |
| SCHEMBL18422910 | 0.67 | CETP (0.39) | — | |
| SCHEMBL2262667 | 0.67 | CETP (0.39) | — | |
| SCHEMBL18422707 | 0.67 | CETP (0.39) | — | |
| SCHEMBL623951 | 0.67 | — | — | |
| SCHEMBL2852867 | 0.67 | CETP (0.39) | — | |
| SCHEMBL199 | 0.67 | CETP (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220144848-A1 | SUBSTITUTED OXOPYRIDINE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2022-05-12 | — | — | US | disclosed |
| EP-2588197-B1 | FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS | GILEAD SCIENCES INC (US) | 2014-11-05 | — | — | EP | disclosed |
| US-8623833-B2 | Compositions and methods for enhancing drug delivery across and into epithelial tissues | KAI PHARMACEUTICALS, INC. (US) | 2014-01-07 | — | — | US | disclosed |
| EP-1786822-A1 | FUSED TRICYCLIC DERIVATIVES FOR THE TREATMENT OF PSYCHOTIC DISORDERS | GLAXO GROUP LIMITED (GB) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006024517-A1 | FUSED TRICYCLIC DERIVATIVES FOR THE TREATMENT OF PSYCHOTIC DISORDERS | GLAXO GROUP LIMITED (GB) | 2006-03-09 | — | — | WO | disclosed |