Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL910730 | 0.82 | — | — | |
| SCHEMBL21137245 | 0.80 | CPN1 (0.38) | CPN1CPB2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8133047 | 0.78 | CPN1 (0.36) | CPN1CPB2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3653310 | 0.78 | CPN1 (0.36) | CPN1CPB2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24170295 | 0.78 | CPN1 (0.36) | CPN1CPB2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1193019 | 0.77 | — | — | |
| SCHEMBL497976 | 0.77 | — | — | |
| SCHEMBL121101 | 0.76 | CPN1 (0.39) | CPN1CPB2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10206052 | 0.76 | CPN1 (0.39) | CPN1CPB2SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL30004842 | 0.76 | SLC6A2 (0.37) | CPN1CPB2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1930139-B | Derivatives of hydroxamic acid as metalloproteinase inhibitors | VERNALIS OXFORD LTD | 2011-07-27 | — | — | CN | disclosed |
| CN-100352806-C | 4-piperidinyl alkylamine derivatives as muscarinic receptor antagonists | HOFFMANN LA ROCHE (CH) | 2007-12-05 | — | — | CN | disclosed |
| EP-1773817-A1 | SUBSTITUTED ARYL-AMINE DERIVATIVES AND METHODS OF USE | Amgen Inc. (US) | 2007-04-18 | — | — | EP | disclosed |
| CN-1930139-A | Derivatives of hydroxamic acid as metalloproteinase inhibitors | VERNALIS OXFORD LTD (GB) | 2007-03-14 | — | — | CN | disclosed |
| WO-2006012374-A1 | SUBSTITUTED ARYL-AMINE DERIVATIVES AND METHODS OF USE | AMGEN INC. (US) | 2006-02-02 | — | — | WO | disclosed |
| CN-1599722-A | 4-piperidinyl alkylamine derivatives as muscarinic receptor antagonists | HOFFMANN LA ROCHE (CH) | 2005-03-23 | — | — | CN | disclosed |