Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5263986 | 0.99 | KCNH2 (0.56) | KCNH2CHRM2DRD1DPP4KDM4E | |
| Hydrochloric Acid SCHEMBL5263989 | 0.99 | KCNH2 (0.56) | KCNH2CHRM2DRD1DPP4KDM4E | |
| SCHEMBL5261875 | 0.91 | KCNH2 (0.46) | KCNH2CHRM2DRD1DPP4KDM4E | |
| SCHEMBL5261280 | 0.87 | KCNH2 (0.65) | KCNH2CHRM2KDM4EHSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL6713218 | 0.87 | KCNH2 (0.64) | KCNH2CHRM2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL7160246 | 0.86 | KCNH2 (0.53) | KCNH2CHRM2DRD1DPP4KDM4E | |
| SCHEMBL4729956 | 0.86 | KCNH2 (0.53) | KCNH2CHRM2DRD1DPP4KDM4E | |
| SCHEMBL5261839 | 0.85 | KCNH2 (0.56) | KCNH2CHRM2DRD1DPP4POLB | |
| SCHEMBL5259905 | 0.85 | KDM4E (0.56) | KCNH2CHRM2DRD1DPP4KDM4E | |
| SCHEMBL4729976 | 0.85 | KCNH2 (0.51) | KCNH2CHRM2DRD1DPP4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187835-B1 | OPTICALLY ACTIVE QUINOLINE CARBOXYLIC ACID DERIVATIVES HAVING 7-PYRROLIDINE SUBSTITUTES CAUSING OPTICAL ACTIVITY AND A PROCESS FOR PREPARING THEREOF | DONG WHA PHARM IND CO LTD (KR) | 2007-12-26 | — | — | EP | claimed |