Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 4/20 | 0.50 |
| ▸ | CTSS | P25774 | 3/20 | 0.50 |
| ▸ | CTSL | P07711 | 2/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.50 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21169229 | 1.00 | CA1 (0.53) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL15250454 | 1.00 | CA1 (0.53) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL19227630 | 0.91 | CA1 (0.58) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL12336373 | 0.88 | CA1 (0.47) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL16591738 | 0.88 | CA1 (0.47) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL9911449 | 0.87 | CA1 (0.52) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL4032796 | 0.86 | CA1 (0.53) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL8560322 | 0.86 | CA1 (0.53) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL272780 | 0.86 | CA1 (0.53) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL8561571 | 0.86 | CA1 (0.53) | CA1CA2CA7CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836161-A2 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | Neurochem (International) Limited (CH) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006085149-A2 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2006-08-17 | — | — | WO | disclosed |