Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4064721 | 0.88 | NAMPT (0.39) | RAB9ACYP17A1NAMPT | |
| SCHEMBL4069107 | 0.88 | NAMPT (0.39) | RAB9ACYP17A1NAMPT | |
| SCHEMBL14195878 | 0.84 | POLB (0.42) | RAB9ANPC1CYP17A1MAPTNAMPT | |
| SCHEMBL4804680 | 0.76 | POLB (0.43) | RAB9ANPC1CYP17A1MAPTNAMPT | |
| SCHEMBL4804689 | 0.76 | POLB (0.43) | RAB9ANPC1CYP17A1MAPTNAMPT | |
| SCHEMBL5262905 | 0.75 | SMN1; SMN2 (0.41) | CYP1A2CYP2C19SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL14291605 | 0.73 | NAMPT (0.43) | RAB9ACYP17A1NAMPT | |
| SCHEMBL5263651 | 0.72 | GAA (0.38) | CYP1A2CYP2C19SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL1197794 | 0.72 | CYP17A1 (0.47) | RAB9ACYP17A1NAMPT | |
| SCHEMBL29957527 | 0.72 | CYP17A1 (0.47) | RAB9ACYP17A1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819332-A2 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES | Prosidion Limited (GB) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006059164-A2 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES | PROSIDION LIMITED (GB) | 2006-06-08 | — | — | WO | disclosed |