Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 10/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5260657 | 0.88 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL5260739 | 0.88 | KCNH2 (0.64) | KCNH2 | |
| Oxalic Acid SCHEMBL5263826 | 0.88 | KCNH2 (0.61) | KCNH2 | |
| SCHEMBL5260199 | 0.83 | KCNH2 (0.76) | KCNH2 | |
| SCHEMBL5264336 | 0.81 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL5260215 | 0.81 | KCNH2 (0.76) | KCNH2 | |
| SCHEMBL5265007 | 0.80 | KCNH2 (0.63) | KCNH2 | |
| SCHEMBL5262423 | 0.79 | KCNH2 (0.59) | KCNH2 | |
| SCHEMBL5263873 | 0.79 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL14341386 | 0.78 | KCNH2 (0.63) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399443-B1 | NITROGEN-CONTAINING BICYCLIC HETEROCYCLES FOR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2007-12-12 | — | — | EP | claimed |