Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELE | P16581 | 8/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 7/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5268197 | 0.86 | MEN1 (0.38) | SELEVCAM1KDM4ETSHRCYP1A2 | |
| SCHEMBL20939332 | 0.81 | CYP2A6 (0.33) | SELEVCAM1MEN1 | |
| SCHEMBL29512111 | 0.77 | MEN1 (0.41) | MEN1KMT2A | |
| SCHEMBL29808187 | 0.75 | MAPK1 (0.35) | LMNASMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL6674194 | 0.75 | MAPK1 (0.35) | LMNASMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL18342663 | 0.71 | EGFR (0.33) | — | |
| SCHEMBL656316 | 0.71 | EGFR (0.36) | — | |
| SCHEMBL7021081 | 0.70 | CYP2A6 (0.68) | SELEVCAM1CYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL5265133 | 0.70 | MEN1 (0.35) | MEN1 | |
| SCHEMBL15935249 | 0.70 | MRGPRX1 (0.38) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844052-A1 | THIENO[2,3-D]PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION | Pharmacia & Upjohn Company LLC (US) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006079916-A1 | THIENO [2,3-D] PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-08-03 | — | — | WO | disclosed |