Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 19/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5264581 | 0.89 | P2RY12 (0.55) | P2RY12MEN1ALDH1A1KMT2A | |
| SCHEMBL5263408 | 0.87 | P2RY12 (0.56) | P2RY12MEN1ALDH1A1KMT2A | |
| SCHEMBL5265651 | 0.87 | P2RY12 (0.65) | P2RY12MEN1 | |
| SCHEMBL5266124 | 0.86 | P2RY12 (0.55) | P2RY12MEN1ALDH1A1KMT2A | |
| SCHEMBL5265973 | 0.85 | P2RY12 (0.63) | P2RY12MEN1 | |
| SCHEMBL5262412 | 0.85 | P2RY12 (0.57) | P2RY12MEN1ALDH1A1KMT2A | |
| SCHEMBL5263732 | 0.85 | P2RY12 (0.60) | P2RY12MEN1ALDH1A1KMT2A | |
| SCHEMBL5267835 | 0.84 | P2RY12 (0.56) | P2RY12MEN1ALDH1A1KMT2A | |
| SCHEMBL5263310 | 0.83 | P2RY12 (0.57) | P2RY12MEN1ALDH1A1KMT2A | |
| SCHEMBL5263662 | 0.83 | P2RY12 (0.55) | P2RY12MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844052-A1 | THIENO[2,3-D]PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION | Pharmacia & Upjohn Company LLC (US) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006079916-A1 | THIENO [2,3-D] PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-08-03 | — | — | WO | disclosed |