Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SALL4 | Q9UJQ4 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 5/20 | 0.42 |
| ▸ | TAF1 | P21675 | 1/20 | 0.42 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GFER | P55789 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5126991 | 0.99 | SALL4 (0.46) | SALL4BRD4TAF1TAF1LADRA1B | |
| SCHEMBL5117561 | 0.90 | SALL4 (0.48) | SALL4BRD4TAF1TAF1LADRA1B | |
| Hydrochloric Acid SCHEMBL5117380 | 0.89 | SALL4 (0.47) | SALL4BRD4TAF1TAF1LADRA1B | |
| SCHEMBL5123390 | 0.89 | SALL4 (0.54) | SALL4BRD4TAF1TAF1LADRA1B | |
| SCHEMBL5268004 | 0.89 | SALL4 (0.47) | SALL4BRD4TAF1TAF1LADRA1B | |
| Hydrochloric Acid SCHEMBL5123940 | 0.88 | BRD4 (0.46) | SALL4BRD4TAF1TAF1LADRA1B | |
| Hydrochloric Acid SCHEMBL5128078 | 0.88 | SALL4 (0.46) | SALL4BRD4TAF1TAF1LADRA1B | |
| SCHEMBL5127402 | 0.87 | SALL4 (0.50) | SALL4BRD4TAF1TAF1LADRA1B | |
| SCHEMBL5122778 | 0.85 | SALL4 (0.45) | SALL4BRD4TAF1TAF1LADRA1B | |
| SCHEMBL5124160 | 0.85 | SALL4 (0.44) | SALL4BRD4TAF1TAF1LADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791840-A1 | SUBSTITUTED BICYCLIC IMIDAZO-3-YLAMINE COMPOUNDS | Grünenthal GmbH (DE) | 2007-06-06 | — | — | EP | claimed |
| WO-2006029980-A1 | SUBSTITUTED BICYCLIC IMIDAZO-3-YLAMINE COMPOUNDS | Grünenthal GmbH (DE) | 2006-03-23 | — | — | WO | claimed |
| EP-1791840-A1 | SUBSTITUTED BICYCLIC IMIDAZO-3-YLAMINE COMPOUNDS | Grünenthal GmbH (DE) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006029980-A1 | SUBSTITUTED BICYCLIC IMIDAZO-3-YLAMINE COMPOUNDS | Grünenthal GmbH (DE) | 2006-03-23 | — | — | WO | disclosed |