Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.33 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5264201 | 1.00 | PDE10A (0.37) | PDE10AADORA2AMEN1KMT2AFGFR4 | |
| SCHEMBL5261405 | 0.93 | PDE10A (0.37) | PDE10AADORA2AMEN1KMT2AFGFR4 | |
| SCHEMBL5261407 | 0.93 | PDE10A (0.37) | PDE10AADORA2AMEN1KMT2AFGFR4 | |
| SCHEMBL5262013 | 0.92 | KMT2A (0.45) | PDE10AADORA2AMEN1KMT2ANPC1 | |
| SCHEMBL5263355 | 0.92 | KMT2A (0.45) | PDE10AADORA2AMEN1KMT2ANPC1 | |
| SCHEMBL5260147 | 0.91 | ADORA2A (0.47) | PDE10AADORA2AMEN1KMT2AFGFR4 | |
| SCHEMBL5260152 | 0.91 | ADORA2A (0.47) | PDE10AADORA2AMEN1KMT2AFGFR4 | |
| SCHEMBL5259332 | 0.89 | ADORA2A (0.37) | PDE10AADORA2AMEN1KMT2AFGFR4 | |
| SCHEMBL5258976 | 0.89 | KMT2A (0.43) | PDE10AADORA2AMEN1KMT2ANPC1 | |
| SCHEMBL5258974 | 0.89 | KMT2A (0.43) | PDE10AADORA2AMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309590-B1 | AZAINDOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS ANTITUMOR AGENTS | PFIZER ITALIA SRL (IT) | 2007-09-19 | — | — | EP | claimed |