Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 15/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 16/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 11/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4468589 | 0.85 | PDE4A (0.54) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL4460010 | 0.81 | PDE4A (0.45) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL13405848 | 0.78 | TP53 (0.56) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL4476124 | 0.76 | PDE4A (0.53) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL4471208 | 0.75 | PDE4A (0.44) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL13405847 | 0.75 | PDE4A (0.46) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL4458833 | 0.75 | HSD17B10 (0.46) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL4465902 | 0.75 | PDE4A (0.44) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL4475738 | 0.75 | PDE4A (0.44) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL13405856 | 0.75 | PDE4A (0.55) | PDE4APDE4DPDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802615-A1 | PHOSPHODIESTERASE 4 INHIBITORS | Memory Pharmaceuticals Corporation (US) | 2007-07-04 | — | — | EP | claimed |
| WO-2006044955-A1 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2006-04-27 | — | — | WO | claimed |