Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1331553 | 0.96 | APP (0.33) | APPEPHX2GRIA1 | |
| SCHEMBL918433 | 0.91 | APP (0.32) | APP | |
| SCHEMBL2167418 | 0.87 | APP (0.34) | APPEPHX2GRIA1 | |
| SCHEMBL14603045 | 0.87 | APP (0.34) | APPEPHX2GRIA1 | |
| SCHEMBL2167415 | 0.87 | APP (0.34) | APPEPHX2GRIA1 | |
| SCHEMBL23001132 | 0.83 | EPHX2 (0.48) | EPHX2 | |
| SCHEMBL23001180 | 0.83 | EPHX2 (0.48) | EPHX2 | |
| SCHEMBL355093 | 0.82 | EPHX2 (0.40) | APPEPHX2 | |
| SCHEMBL355130 | 0.82 | MEN1 (0.36) | APPEPHX2GRIA1 | |
| SCHEMBL353305 | 0.82 | EPHX2 (0.40) | APPEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836161-A2 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | Neurochem (International) Limited (CH) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006085149-A2 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2006-08-17 | — | — | WO | disclosed |