Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 16/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5263401 | 0.92 | P2RY12 (0.67) | P2RY12MEN1HTR6 | |
| SCHEMBL5263847 | 0.91 | P2RY12 (0.64) | P2RY12MEN1HTR6 | |
| SCHEMBL5268223 | 0.90 | P2RY12 (0.64) | P2RY12MEN1HTR6 | |
| SCHEMBL5265242 | 0.89 | P2RY12 (0.66) | P2RY12MEN1HTR6 | |
| SCHEMBL5268538 | 0.88 | P2RY12 (0.67) | P2RY12MEN1HTR6 | |
| SCHEMBL5266981 | 0.88 | P2RY12 (0.62) | P2RY12MEN1HTR6 | |
| SCHEMBL5263993 | 0.88 | P2RY12 (0.66) | P2RY12MEN1HTR6 | |
| SCHEMBL5316455 | 0.87 | P2RY12 (0.65) | P2RY12MEN1HTR6 | |
| SCHEMBL5266906 | 0.87 | P2RY12 (0.67) | P2RY12MEN1 | |
| SCHEMBL5269741 | 0.86 | P2RY12 (0.62) | P2RY12MEN1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844052-A1 | THIENO[2,3-D]PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION | Pharmacia & Upjohn Company LLC (US) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006079916-A1 | THIENO [2,3-D] PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-08-03 | — | — | WO | disclosed |