Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.48 |
| ▸ | DYRK3 | O43781 | 3/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.48 |
| ▸ | EGFR | P00533 | 3/20 | 0.48 |
| ▸ | PIM1 | P11309 | 3/20 | 0.48 |
| ▸ | CLK2 | P49760 | 3/20 | 0.48 |
| ▸ | IRAK1 | P51617 | 3/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.48 |
| ▸ | MAP4K2 | Q12851 | 3/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.48 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.48 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.48 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.48 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2186218 | 0.85 | DYRK3 (0.63) | HTTSMN1; SMN2RAB9AAURKBDYRK3 | |
| SCHEMBL12392647 | 0.82 | DYRK3 (0.50) | HTTSMN1; SMN2RAB9AAURKBDYRK3 | |
| SCHEMBL12392593 | 0.82 | DYRK3 (0.49) | HTTSMN1; SMN2RAB9AAURKBDYRK3 | |
| SCHEMBL13841685 | 0.81 | DYRK3 (0.45) | HTTSMN1; SMN2RAB9AAURKBDYRK3 | |
| SCHEMBL3868621 | 0.81 | DYRK3 (0.45) | HTTSMN1; SMN2RAB9AAURKBDYRK3 | |
| SCHEMBL13841735 | 0.80 | PIP4K2C (0.38) | HTTSMN1; SMN2RAB9AAURKBDYRK3 | |
| SCHEMBL1160807 | 0.80 | DYRK3 (0.44) | HTTSMN1; SMN2RAB9AAURKBDYRK3 | |
| SCHEMBL12392367 | 0.80 | EGFR (0.50) | HTTSMN1; SMN2RAB9AAURKBDYRK3 | |
| SCHEMBL12392659 | 0.79 | HTT (0.46) | HTTSMN1; SMN2RAB9AAURKBDYRK3 | |
| SCHEMBL13841601 | 0.79 | SMN1; SMN2 (0.49) | HTTSMN1; SMN2RAB9AAURKBDYRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8008487-B2 | Substituted thieno[2,3-D]pyrimidines as fungicides | DOW AGROSCIENCES LLC (US) | 2011-08-30 | — | — | US | disclosed |
| US-8008487-B2 | Substituted thieno[2,3-D]pyrimidines as fungicides | DOW AGROSCIENCES LLC (US) | 2011-08-30 | — | — | US | disclosed |
| EP-1802632-A1 | THIENO-PYRIMIDINE COMPOUNDS HAVING FUNGICIDAL ACTIVITY | Dow AgroSciences LLC (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006047397-A1 | THIENO-PYRIMIDINE COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2006-05-04 | — | — | WO | disclosed |