Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2534399 | 0.93 | PLK1 (0.68) | PLK1 | |
| SCHEMBL2534402 | 0.93 | PLK1 (0.68) | PLK1 | |
| SCHEMBL2496987 | 0.92 | PLK1 (0.56) | PLK1 | |
| SCHEMBL2496985 | 0.84 | PLK1 (0.41) | PLK1 | |
| SCHEMBL2519135 | 0.81 | PLK1 (0.79) | PLK1 | |
| SCHEMBL2519132 | 0.81 | PLK1 (0.79) | PLK1 | |
| SCHEMBL2521623 | 0.80 | PLK1 (0.72) | PLK1 | |
| SCHEMBL2521625 | 0.80 | PLK1 (0.72) | PLK1 | |
| SCHEMBL2521944 | 0.77 | PLK1 (0.67) | PLK1 | |
| SCHEMBL2521930 | 0.77 | PLK1 (0.67) | PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1813613-B1 | NOVEL FUSED IMIDAZOLE DERIVATIVE | MSD KK (JP) | 2012-12-19 | — | — | EP | disclosed |
| EP-1813613-A1 | NOVEL FUSED IMIDAZOLE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-08-01 | — | — | EP | disclosed |