Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3523360 | 0.93 | MAPK14 (0.49) | MAPK14 | |
| SCHEMBL3522797 | 0.90 | MAPK14 (0.56) | MAPK14 | |
| SCHEMBL3523334 | 0.90 | MAPK14 (0.67) | MAPK14 | |
| SCHEMBL5267652 | 0.89 | MAPK14 (0.54) | MAPK14 | |
| SCHEMBL5264919 | 0.88 | MAPK14 (0.51) | MAPK14 | |
| SCHEMBL3521651 | 0.87 | MAPK14 (0.53) | MAPK14 | |
| SCHEMBL3519053 | 0.87 | MAPK14 (0.52) | MAPK14 | |
| SCHEMBL5429413 | 0.85 | MAPK14 (0.51) | MAPK14 | |
| SCHEMBL3523763 | 0.85 | MAPK14 (0.53) | MAPK14 | |
| SCHEMBL3519211 | 0.85 | MAPK14 (0.53) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753731-A2 | PYRIMIDIN-4-ONE DERIVATIVES AND THEIR USE AS P38 KINASE MODULATORS | Pharmacia Corporation (US) | 2007-02-21 | — | — | EP | disclosed |
| WO-2004087677-A2 | PYRIMIDIN-4-ONE DERIVATIVES AND THEIR USE AS P38 KINASE MODULATORS | PHARMACIA CORPORATION (US) | 2004-10-14 | — | — | WO | disclosed |