Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 20/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592431 | 0.91 | P2RY12 (0.70) | P2RY12CYP2C9CYP3A4CHRM2DRD3 | |
| SCHEMBL4097402 | 0.89 | P2RY12 (0.71) | P2RY12CYP2C9CYP3A4CHRM2DRD3 | |
| SCHEMBL4103594 | 0.89 | P2RY12 (0.88) | P2RY12CYP2C9CYP3A4CHRM2DRD3 | |
| SCHEMBL5267633 | 0.88 | P2RY12 (0.69) | P2RY12CYP2C9CYP3A4CHRM2DRD3 | |
| SCHEMBL5264767 | 0.84 | P2RY12 (0.80) | P2RY12CYP2C9CYP3A4CHRM2DRD3 | |
| SCHEMBL4109134 | 0.84 | P2RY12 (0.82) | P2RY12CYP2C9CYP3A4CHRM2DRD3 | |
| SCHEMBL4109942 | 0.84 | P2RY12 (0.81) | P2RY12CYP2C9CYP3A4CHRM2DRD3 | |
| SCHEMBL4097854 | 0.84 | P2RY12 (1.00) | P2RY12CYP2C9CYP3A4CHRM2DRD3 | |
| SCHEMBL5059115 | 0.83 | P2RY12 (0.76) | P2RY12CYP2C9CYP3A4CHRM2DRD3 | |
| SCHEMBL4098557 | 0.82 | P2RY12 (0.69) | P2RY12CYP2C9CYP3A4CHRM2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836189-A1 | NOVEL PYRIDINE COMPOUNDS | AstraZeneca AB (SE) | 2007-09-26 | — | — | EP | claimed |
| WO-2006073361-A1 | NOVEL PYRIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2006-07-13 | — | — | WO | claimed |