Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 15/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5264557 | 1.00 | P2RY12 (0.47) | P2RY12MEN1CNR2ALDH1A1LMNA | |
| SCHEMBL5268162 | 0.93 | P2RY12 (0.49) | P2RY12MEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5270277 | 0.93 | P2RY12 (0.49) | P2RY12MEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5268191 | 0.88 | P2RY12 (0.63) | P2RY12MEN1 | |
| SCHEMBL5265212 | 0.87 | P2RY12 (0.52) | P2RY12MEN1 | |
| SCHEMBL5262781 | 0.87 | P2RY12 (0.52) | P2RY12MEN1 | |
| SCHEMBL5267805 | 0.85 | P2RY12 (0.49) | P2RY12MEN1CNR2TSHRHTT | |
| SCHEMBL4895006 | 0.83 | P2RY12 (0.53) | P2RY12 | |
| SCHEMBL4896996 | 0.83 | P2RY12 (0.53) | P2RY12 | |
| SCHEMBL5268538 | 0.76 | P2RY12 (0.67) | P2RY12MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844052-A1 | THIENO[2,3-D]PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION | Pharmacia & Upjohn Company LLC (US) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006079916-A1 | THIENO [2,3-D] PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-08-03 | — | — | WO | disclosed |