SCHEMBL5265634

SCHEMBL5265634

CC(=NO)C(=NO)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.54
CYP2C19 P33261 1/20 0.54
HSD17B10 Q99714 2/20 0.44
SMN1; SMN2 Q16637 3/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
ALDH1A1 P00352 3/20 0.40
HPGD P15428 1/20 0.39
GFER P55789 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
KDM4E B2RXH2 2/20 0.38
MAPT P10636 2/20 0.38
MEN1 O00255 1/20 0.38
GLA P06280 1/20 0.38
KMT2A Q03164 1/20 0.38
LMNA P02545 1/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5265637 1.00 GAA (0.54) GAACYP2C19HSD17B10SMN1; SMN2NPC1
SCHEMBL17973397 0.87 SMN1; SMN2 (0.50) GAACYP2C19HSD17B10SMN1; SMN2NPC1
SCHEMBL7760450 0.85 GAA (0.48) GAACYP2C19HSD17B10SMN1; SMN2NPC1
SCHEMBL7760451 0.85 GAA (0.48) GAACYP2C19HSD17B10SMN1; SMN2NPC1
SCHEMBL7757269 0.83 GAA (0.42) GAACYP2C19HSD17B10SMN1; SMN2NPC1
SCHEMBL12131284 0.82 GAA (0.65) GAACYP2C19HSD17B10SMN1; SMN2NPC1
SCHEMBL3892921 0.82 GAA (0.65) GAACYP2C19HSD17B10SMN1; SMN2NPC1
SCHEMBL189919 0.82 GAA (0.65) GAACYP2C19HSD17B10SMN1; SMN2NPC1
SCHEMBL6060474 0.82 GAA (0.65) GAACYP2C19HSD17B10SMN1; SMN2NPC1
SCHEMBL189920 0.82 GAA (0.65) GAACYP2C19HSD17B10SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4098991-A REMOVAL OF CATALYTIC RESIDUES FROM HYDROGENATED THERMOPLASTIC OR ELASTOMERIC POLYMERS THE FIRESTONE TIRE & RUBBER COMPANY (US) 1978-07-04 US claimed
CN-111244547-B Electrolyte containing aromatic oxime additive and preparation method and application thereof 四川虹微技术有限公司 2021-09-17 CN disclosed
CN-111244547-A Electrolyte containing aromatic oxime additive and preparation method and application thereof 四川虹微技术有限公司 2020-06-05 CN disclosed
WO-2015082592-A2 METHOD FOR PREPARING AMINOARYLBORANE COMPOUNDS OR DERIVATIVES THEREOF Universite de Bordeaux (FR) 2015-06-11 WO disclosed
EP-2881398-A1 Method for preparing aminoarylborane compounds or derivatives thereof Université de Bordeaux I (FR) 2015-06-10 EP disclosed
EP-1221447-B1 Alkyl Cobalt (III) Dioximates and process for forming the same DU PONT (US) 2007-10-03 EP disclosed
US-6858745-B2 Alkyl cobalt (III) dioximates and process for forming the same E. I. DU PONT DE NEMOURS AND COMPANY (US) 2005-02-22 US disclosed
US-6740618-B2 REACTIN A GLYOXIME, A COBALT SALT, AN UNSATURATED COMPOUND SUCH AS AN ALKYL ACRYLATE, AND A LEWIS BASE IN H2; USE AS A POLYMERIZATION CATALYST, ESPECIALLY IN POLYMERIZING METHYL METHACRYLATE E. I. DU PONT DE NEMOURS AND COMPANY 2004-05-25 US disclosed
US-6713427-B2 TREATING A MIXTURE OF A COBALT (II) SALT, A DIOXIME OF THE FORMULA R1-C( HORIZONTAL-LINE NOH)-C( HORIZONTAL-LINE NOH)-R2, AN ACRYLIC ESTER, A LEWIS BASE WITH MOLECULAR HYDROGEN TO FORM A COBALT DIOXIMATE COMPLEX E. I. DU PONT DE NEMOURS AND COMPANY 2004-03-30 US disclosed
US-20030149275-A1 Alkyl cobalt (III) dioximates and process for forming the same AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) 2003-08-07 US disclosed
EP-1221447-A2 Alkyl Cobalt (III) Dioximates and process for forming the same E. I. du Pont de Nemours and Company (US) 2002-07-10 EP disclosed
US-20020087006-A1 Alkyl cobalt (III) dioximates and process for forming the same AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) 2002-07-04 US disclosed
US-5977399-A Iminooxymethyleneanilides, preparation thereof and intermediates therefor, and compositions containing them BASF AKTIENGESELLSCHAFT (DE) 1999-11-02 US disclosed
EP-0793645-B1 IMINOOXYMETHYLENE ANILIDES, PROCESS AND INTERMEDIATE PRODUCTS FOR PREPARING THE SAME AND PESTICIDES CONTAINING THE SAME BASF AG (DE) 1999-04-28 EP disclosed
EP-0306538-A1 PROCESS FOR PREPARING ALPHA-(3-BENZYLPHENYL)PROPIONIC ACID DERIVATIVE NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-03-15 EP disclosed
US-4721734-A PHOTOPOLYMERIZATION OF UNSATURATED COMPOUNDS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1988-01-26 US disclosed
US-4477681-A PHOTOPOLYMERIZATION AND HARDENING OF PRINTING DYES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1984-10-16 US disclosed
US-4347111-A PHOTOPOLYMERIZATION OF UNSATURATED COMPOUNDS, HARDENING OF PRINTING DYES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1982-08-31 US disclosed
US-4098991-A REMOVAL OF CATALYTIC RESIDUES FROM HYDROGENATED THERMOPLASTIC OR ELASTOMERIC POLYMERS THE FIRESTONE TIRE & RUBBER COMPANY (US) 1978-07-04 US disclosed
US-4020108-A CATALYSTS SCM CORPORATION (US) 1977-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030149275-A1 Alkyl cobalt (III) dioximates and process for forming the same CCR3, CBR3, CCR6 GAA 4343/4885CYP2C19 2755/4885HSD17B10 873/4885
US-20020087006-A1 Alkyl cobalt (III) dioximates and process for forming the same CCR3, CBR3, CCR6 GAA 4331/4885CYP2C19 2760/4885HSD17B10 882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.