Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 3/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | PTAFR | P25105 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5264893 | 0.92 | GNRHR (0.38) | GNRHRCACNA1FCHRM4ADORA3CHRM1 | |
| SCHEMBL5271265 | 0.87 | GNRHR (0.46) | GNRHRCACNA1FCHRM4ADORA3CHRM1 | |
| SCHEMBL5266705 | 0.85 | GNRHR (0.46) | GNRHRCACNA1FCHRM4ADORA3CHRM1 | |
| SCHEMBL5265320 | 0.85 | S1PR4 (0.39) | GNRHRFPR1GPR183GPR119 | |
| SCHEMBL5315362 | 0.84 | GNRHR (0.56) | GNRHRCACNA1FCHRM4ADORA3CHRM1 | |
| SCHEMBL5266691 | 0.84 | GNRHR (0.62) | GNRHRCACNA1FCHRM4ADORA3CHRM1 | |
| SCHEMBL5264693 | 0.83 | GNRHR (0.46) | GNRHRCACNA1FCHRM4ADORA3CHRM1 | |
| SCHEMBL5264279 | 0.81 | GNRHR (0.48) | GNRHRCACNA1FCHRM4ADORA3CHRM1 | |
| SCHEMBL5267932 | 0.80 | GNRHR (0.40) | GNRHRCACNA1FCHRM4ADORA3CHRM1 | |
| SCHEMBL5263977 | 0.80 | GNRHR (0.40) | GNRHRCACNA1FCHRM4ADORA3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648906-B1 | ORGANOSILICON COMPOUNDS AND THEIR USE | TAKEDA CAMBRIDGE LTD (GB) | 2007-10-03 | — | — | EP | claimed |