Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 17/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315484 | 1.00 | P2RY12 (0.58) | P2RY12MEN1HTR6 | |
| SCHEMBL5262993 | 0.87 | P2RY12 (0.59) | P2RY12MEN1 | |
| SCHEMBL5265801 | 0.87 | P2RY12 (0.59) | P2RY12MEN1 | |
| SCHEMBL4886442 | 0.83 | P2RY12 (0.64) | P2RY12MEN1 | |
| SCHEMBL4894985 | 0.83 | P2RY12 (0.64) | P2RY12MEN1 | |
| SCHEMBL5264486 | 0.81 | P2RY12 (0.66) | P2RY12MEN1HTR6 | |
| SCHEMBL4895654 | 0.81 | P2RY12 (0.61) | P2RY12 | |
| SCHEMBL4895692 | 0.81 | P2RY12 (0.61) | P2RY12 | |
| SCHEMBL5263401 | 0.81 | P2RY12 (0.67) | P2RY12MEN1HTR6 | |
| SCHEMBL5268538 | 0.81 | P2RY12 (0.67) | P2RY12MEN1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844052-A1 | THIENO[2,3-D]PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION | Pharmacia & Upjohn Company LLC (US) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006079916-A1 | THIENO [2,3-D] PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-08-03 | — | — | WO | disclosed |