Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | PPARA | Q07869 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | TTR | P02766 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | PPARG | P37231 | 1/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.60 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.60 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5929495 | 0.93 | TSHR (0.67) | TSHRTDP1CYP2C9PPARASMN1; SMN2 | |
| SCHEMBL89387 | 0.92 | TSHR (0.62) | TSHRTDP1CYP2C9PPARASMN1; SMN2 | |
| SCHEMBL20006078 | 0.90 | TSHR (0.60) | TSHRTDP1CYP2C9PPARASMN1; SMN2 | |
| SCHEMBL10241943 | 0.90 | TSHR (0.64) | TSHRTDP1CYP2C9PPARASMN1; SMN2 | |
| SCHEMBL13697 | 0.88 | TSHR (0.62) | TSHRTDP1CYP2C9PPARASMN1; SMN2 | |
| SCHEMBL13475545 | 0.88 | TSHR (0.62) | TSHRTDP1CYP2C9PPARASMN1; SMN2 | |
| SCHEMBL5223212 | 0.88 | TSHR (0.62) | TSHRTDP1CYP2C9PPARASMN1; SMN2 | |
| SCHEMBL8302732 | 0.88 | TSHR (0.67) | TSHRTDP1CYP2C9PPARASMN1; SMN2 | |
| SCHEMBL172302 | 0.87 | TSHR (0.61) | TSHRTDP1CYP2C9PPARASMN1; SMN2 | |
| SCHEMBL6738557 | 0.86 | TSHR (0.60) | TSHRTDP1CYP2C9PPARASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406577-B1 | NOVEL COUPLER COMPONENTS FOR OXIDATIVE HAIR COLOURING | HENKEL KGAA (DE) | 2007-10-10 | — | — | EP | disclosed |
| EP-1406577-A1 | NOVEL COUPLER COMPONENTS FOR OXIDATIVE HAIR COLOURING | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-04-14 | — | — | EP | disclosed |
| WO-2002100364-A1 | NOVEL COUPLER COMPONENTS FOR OXIDATIVE HAIR COLOURING | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-12-19 | — | — | WO | disclosed |