Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 19/20 | 0.90 |
| ▸ | CYSLTR1 | Q9Y271 | 19/20 | 0.90 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5266726 | 1.00 | CYSLTR2 (0.90) | CYSLTR2CYSLTR1PPARA | |
| SCHEMBL3622042 | 0.94 | CYSLTR2 (0.83) | CYSLTR2CYSLTR1PPARA | |
| SCHEMBL3622044 | 0.94 | CYSLTR2 (0.83) | CYSLTR2CYSLTR1PPARA | |
| SCHEMBL3563429 | 0.93 | CYSLTR2 (0.78) | CYSLTR2CYSLTR1PPARA | |
| SCHEMBL3563434 | 0.93 | CYSLTR2 (0.78) | CYSLTR2CYSLTR1PPARA | |
| SCHEMBL3563436 | 0.93 | CYSLTR2 (0.78) | CYSLTR2CYSLTR1PPARA | |
| SCHEMBL3567214 | 0.92 | CYSLTR2 (0.81) | CYSLTR2CYSLTR1PPARA | |
| SCHEMBL3567209 | 0.92 | CYSLTR2 (0.81) | CYSLTR2CYSLTR1PPARA | |
| SCHEMBL3563171 | 0.92 | CYSLTR2 (0.80) | CYSLTR2CYSLTR1 | |
| SCHEMBL3570636 | 0.92 | CYSLTR2 (0.80) | CYSLTR2CYSLTR1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1852420-B1 | Indole compounds for treating respiratory disorders | ONO PHARMACEUTICAL CO (JP) | 2012-10-17 | — | — | EP | disclosed |
| EP-1852420-A1 | INDOLE COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-11-07 | — | — | EP | disclosed |