Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2 | P11137 | 12/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.42 |
| ▸ | KDR | P35968 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3879170 | 0.80 | MAP2 (0.72) | MAP2GAAKDM4EALDH1A1HPGD | |
| SCHEMBL3878005 | 0.78 | KDR (0.60) | MAP2GAAKDM4EALDH1A1HPGD | |
| SCHEMBL5268201 | 0.77 | KDR (0.52) | MAP2GAAKDM4EALDH1A1HPGD | |
| SCHEMBL3883640 | 0.77 | MAP2 (0.63) | MAP2GAAKDM4EALDH1A1HPGD | |
| SCHEMBL3880397 | 0.76 | MAP2 (0.59) | MAP2GAAKDM4EALDH1A1HPGD | |
| SCHEMBL3877589 | 0.76 | STING1 (0.57) | MAP2HPGDPDGFRBKDR | |
| SCHEMBL3878302 | 0.76 | MAP2 (0.55) | MAP2GAAKDM4EALDH1A1HPGD | |
| SCHEMBL3879403 | 0.74 | MAP2 (0.63) | MAP2GAAKDM4EALDH1A1HPGD | |
| SCHEMBL3884472 | 0.74 | MAP2 (0.63) | MAP2GAAKDM4EALDH1A1HPGD | |
| SCHEMBL3879937 | 0.74 | KDR (0.55) | MAP2GAAKDM4EALDH1A1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841762-A1 | SUBSTITUTED INDOLES, COMPOSITIONS CONTAINING THEM, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE | Aventis Pharma S.A. (FR) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006061493-A1 | SUBSTITUTED INDOLES, COMPOSITIONS CONTAINING THEM, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE | AVENTIS PHARMA S.A. (FR) | 2006-06-15 | — | — | WO | disclosed |