Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Benzyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 known ✓ | P35228 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzyl Alcohol SCHEMBL1047215 | 0.95 | TSHR (0.74) | TSHRALDH1A1LMNACES2CES1 | |
| Benzyl Alcohol SCHEMBL27990015 | 0.93 | TSHR (0.70) | TSHRALDH1A1LMNACES2CES1 | |
| Benzyl Alcohol SCHEMBL27278012 | 0.91 | TSHR (0.67) | TSHRALDH1A1LMNACES2CES1 | |
| Benzyl Alcohol SCHEMBL11421123 | 0.91 | TSHR (0.67) | TSHRALDH1A1LMNACES2CES1 | |
| Benzyl Alcohol SCHEMBL11076018 | 0.90 | TSHR (0.74) | TSHRALDH1A1LMNACES2CES1 | |
| Benzyl Alcohol SCHEMBL1234662 | 0.90 | TSHR (0.74) | TSHRALDH1A1LMNACES2CES1 | |
| Benzyl Alcohol SCHEMBL1234659 | 0.90 | TSHR (0.74) | TSHRALDH1A1LMNACES2CES1 | |
| Benzyl Alcohol SCHEMBL6477897 | 0.90 | TSHR (0.82) | TSHRCES2CES1AKR1B1LTA4H | |
| Benzyl Alcohol SCHEMBL5039741 | 0.86 | TSHR (0.61) | TSHRALDH1A1LMNACES2CES1 | |
| Benzyl Alcohol SCHEMBL11137293 | 0.86 | TSHR (0.61) | TSHRALDH1A1LMNACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1840099-A2 | Mixture for preparing hydrophobic preparation, procedure of manufacturing thereof and utilization thereof | Izonil Slovakia, s.r.o. (SK) | 2007-10-03 | — | — | EP | disclosed |
| US-20070175366-A1 | Mixture for preparing hydrophobic preparation, procedure of manufacturing thereof and utilization thereof | IZONIL SLOVAKIA, S.R.O. (SK) | 2007-08-02 | — | — | US | disclosed |