Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3526714 | 0.99 | MAPK14 (0.54) | MAPK14PARP1 | |
| SCHEMBL3522736 | 0.93 | MAPK14 (0.57) | MAPK14 | |
| SCHEMBL3527013 | 0.92 | MAPK14 (0.56) | MAPK14 | |
| SCHEMBL5266414 | 0.92 | MAPK14 (0.53) | MAPK14PARP1 | |
| SCHEMBL3526853 | 0.91 | MAPK14 (0.54) | MAPK14 | |
| Hydrochloric Acid SCHEMBL3526994 | 0.91 | MAPK14 (0.52) | MAPK14PARP1 | |
| SCHEMBL3518598 | 0.87 | MAPK14 (0.53) | MAPK14 | |
| SCHEMBL3522259 | 0.86 | MAPK14 (0.61) | MAPK14 | |
| SCHEMBL6829445 | 0.86 | MAPK14 (0.74) | MAPK14 | |
| SCHEMBL3520442 | 0.86 | MAPK14 (0.73) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753731-A2 | PYRIMIDIN-4-ONE DERIVATIVES AND THEIR USE AS P38 KINASE MODULATORS | Pharmacia Corporation (US) | 2007-02-21 | — | — | EP | disclosed |
| WO-2004087677-A2 | PYRIMIDIN-4-ONE DERIVATIVES AND THEIR USE AS P38 KINASE MODULATORS | PHARMACIA CORPORATION (US) | 2004-10-14 | — | — | WO | disclosed |