SCHEMBL5267486

SCHEMBL5267486

CCc1cc2c(N3CCN(C(=O)c4ccc(-c5ccccc5)cc4)CC3)nc(OCC(CO)CO)nc2s1

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
P2RY12 Q9H244 20/20 0.67
MEN1 O00255 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5264479 0.90 P2RY12 (0.65) P2RY12MEN1
SCHEMBL5263713 0.88 P2RY12 (0.70) P2RY12MEN1
SCHEMBL5263923 0.88 P2RY12 (0.70) P2RY12MEN1
SCHEMBL5265493 0.88 P2RY12 (0.71) P2RY12MEN1
SCHEMBL5265434 0.88 P2RY12 (0.70) P2RY12MEN1
SCHEMBL5265651 0.87 P2RY12 (0.65) P2RY12MEN1
SCHEMBL5267966 0.87 P2RY12 (0.68) P2RY12MEN1
SCHEMBL5268366 0.87 P2RY12 (0.69) P2RY12MEN1
SCHEMBL5267786 0.87 P2RY12 (0.64) P2RY12MEN1
SCHEMBL5263871 0.86 P2RY12 (0.64) P2RY12MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1844052-A1 THIENO[2,3-D]PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION Pharmacia & Upjohn Company LLC (US) 2007-10-17 EP disclosed
WO-2006079916-A1 THIENO [2,3-D] PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION PHARMACIA & UPJOHN COMPANY LLC (US) 2006-08-03 WO disclosed