Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5264991 | 0.93 | F10 (0.46) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5266030 | 0.91 | F10 (0.44) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5317437 | 0.91 | F10 (0.44) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5318354 | 0.90 | F10 (0.43) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5266099 | 0.89 | F10 (0.43) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13632178 | 0.89 | F10 (0.54) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4500387 | 0.89 | F10 (0.54) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4509377 | 0.89 | F10 (0.54) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5270366 | 0.89 | F10 (0.44) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5265436 | 0.89 | F10 (0.45) | F10CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836198-A1 | SUBSTITUTED PYRROLIDINONES HAVING AN ANTITHROMBOTIC EFFECT, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2007-09-26 | — | — | EP | claimed |
| WO-2006069946-A1 | SUBSTITUTED PYRROLIDINONES HAVING AN ANTITHROMBOTIC EFFECT, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-07-06 | — | — | WO | claimed |