Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 20/20 | 0.69 |
| ▸ | TACR2 | P21452 | 1/20 | 0.58 |
| ▸ | CNR2 | P34972 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1380828 | 1.00 | CNR1 (0.69) | CNR1TACR2CNR2 | |
| SCHEMBL3846966 | 0.92 | CNR1 (0.79) | CNR1TACR2CNR2 | |
| SCHEMBL3845283 | 0.86 | CNR1 (0.84) | CNR1TACR2CNR2 | |
| SCHEMBL5918463 | 0.86 | CNR1 (0.84) | CNR1TACR2CNR2 | |
| SCHEMBL3848299 | 0.86 | CNR1 (0.84) | CNR1TACR2CNR2 | |
| SCHEMBL1381869 | 0.84 | CNR1 (0.84) | CNR1TACR2CNR2 | |
| SCHEMBL5348881 | 0.84 | CNR1 (0.84) | CNR1TACR2CNR2 | |
| SCHEMBL3848484 | 0.83 | CNR1 (0.71) | CNR1TACR2CNR2 | |
| SCHEMBL1376863 | 0.83 | CNR1 (0.83) | CNR1TACR2CNR2 | |
| SCHEMBL2703819 | 0.82 | CNR1 (0.77) | CNR1TACR2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1868999-A1 | PYRIDINE-3-CARBOXAMIDE DERIVATIVES AS CB1 INVERSE AGONISTS | F. Hoffmann-Roche AG (CH) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006106054-A1 | PYRIDINE-3-CARBOXAMIDE DERIVATIVES AS CB1 INVERSE AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-10-12 | — | — | WO | disclosed |