Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 5/20 | 0.59 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.59 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.59 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.59 |
| ▸ | P2RY1 | P47900 | 7/20 | 0.56 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.56 |
| ▸ | SRC | P12931 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.55 |
| ▸ | MACROD2 | A1Z1Q3 | 1/20 | 0.53 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.53 |
| ▸ | MACROD1 | Q9BQ69 | 1/20 | 0.53 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.53 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.51 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.51 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.51 |
| ▸ | ENTPD1 | P49961 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438672 | 0.88 | P2RX1 (0.63) | P2RX1P2RX3P2RX4P2RX2P2RY1 | |
| SCHEMBL30570921 | 0.88 | P2RX1 (0.63) | P2RX1P2RX3P2RX4P2RX2P2RY1 | |
| SCHEMBL11031781 | 0.87 | P2RX1 (0.62) | P2RX1P2RX3P2RX4P2RX2P2RY1 | |
| SCHEMBL30777206 | 0.86 | P2RX1 (0.61) | P2RX1P2RX3P2RX4P2RX2P2RY1 | |
| SCHEMBL28390621 | 0.86 | P2RX1 (0.61) | P2RX1P2RX3P2RX4P2RX2P2RY1 | |
| SCHEMBL30697341 | 0.86 | P2RX1 (0.61) | P2RX1P2RX3P2RX4P2RX2P2RY1 | |
| SCHEMBL1085901 | 0.86 | P2RX1 (0.59) | P2RX1P2RX3P2RX4P2RX2P2RY1 | |
| SCHEMBL28561820 | 0.86 | P2RX1 (0.60) | P2RX1P2RX3P2RX4P2RX2P2RY1 | |
| SCHEMBL30275537 | 0.86 | P2RX1 (0.60) | P2RX1P2RX3P2RX4P2RX2P2RY1 | |
| SCHEMBL8441720 | 0.85 | P2RX1 (0.58) | P2RX1P2RX3P2RX4P2RX2P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1624753-A4 | PURINERGIC MODULATION OF SMELL | UNIV UTAH RES FOUND (US) | 2007-11-07 | — | — | EP | disclosed |
| EP-1624753-A2 | PURINERGIC MODULATION OF SMELL | The University of Utah Research Foundation (US) | 2006-02-15 | — | — | EP | disclosed |
| WO-2004047749-A2 | PURINERGIC MODULATION OF SMELL | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2004-06-10 | — | — | WO | disclosed |