Tolylfluanid

Tolylfluanid

SCHEMBL5268334

CN(C)S(=O)(=O)N(SC(F)(Cl)Cl)c1ccccc1.Cc1ccc(N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C)cc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.41
CA9 Q16790 2/20 0.41
CDK1 P06493 1/20 0.39
CCNB1 P14635 1/20 0.39
CCNA2 P20248 1/20 0.39
CCND1 P24385 1/20 0.39
CDK2 P24941 1/20 0.39
CDK7 P50613 1/20 0.39
CCNH P51946 1/20 0.39
CCNA1 P78396 1/20 0.39
CDK6 Q00534 1/20 0.39
MAPT P10636 4/20 0.34
ALDH1A1 P00352 4/20 0.34
L3MBTL1 Q9Y468 3/20 0.34
TDP1 Q9NUW8 3/20 0.34
POLB P06746 3/20 0.34
TP53 P04637 2/20 0.34
MCOLN3 Q8TDD5 1/20 0.34
CNR2 P34972 1/20 0.34
HTT P42858 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tolylfluanid SCHEMBL21309 0.94 CDK1 (0.42) CA12CA9CDK1CCNB1CCNA2
Dichlofluanid SCHEMBL20684 0.93 POLB (0.38) CA12CA9MAPTALDH1A1L3MBTL1
Dichlofluanid SCHEMBL13858863 0.93 POLB (0.38) CA12CA9MAPTALDH1A1L3MBTL1
Dichlofluanid SCHEMBL27504391 0.91 POLB (0.37) CA12CA9MAPTALDH1A1L3MBTL1
SCHEMBL11370986 0.83 CDK1 (0.40) CA12CA9CDK1CCNB1CCNA2
Dichlofluanid SCHEMBL19032731 0.82 GSK3B (0.38) MAPTALDH1A1L3MBTL1TDP1POLB
SCHEMBL11383718 0.81 MEN1 (0.38) CA12CA9MAPTALDH1A1L3MBTL1
SCHEMBL11382375 0.81 POLB (0.36) CA12CA9MAPTALDH1A1L3MBTL1
SCHEMBL11382249 0.81 POLB (0.36) CA12CA9MAPTALDH1A1L3MBTL1
Dichlofluanid SCHEMBL28059552 0.80 MAPT (0.30) MAPTALDH1A1L3MBTL1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1765072-A1 USE OF PHOSPHATED ALCANOLS AS DISPERSANTS, EMULSIFIERS, HYDROTROPES, WETTING AGENTS AND COMPATABILITY AGENTS IN AGRICULTURAL COMPOSITIONS Akzo Nobel N.V. (NL) 2007-03-28 EP disclosed
WO-2006019772-A1 USE OF PHOSPHATED ALCANOLS AS DISPERSANTS, EMULSIFIERS, HYDROTROPES, WETTING AGENTS AND COMPATABILITY AGENTS IN AGRICULTURAL COMPOSITIONS AKZO NOBEL N.V. (NL) 2006-02-23 WO disclosed
EP-0455287-B1 Fungicidal compounds and compositions containing tris(aryl)-phosphonium salts SHELL INT RESEARCH (NL) 1995-08-02 EP disclosed