SCHEMBL5268524

SCHEMBL5268524

Cc1c(CCCC(=O)O)c2cccc(C=Cc3ccc(OC/C=C/COc4c(F)cccc4F)cc3)c2n1CC(=O)O

nearest known ligand 0.73

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 20/20 0.73
CYSLTR1 Q9Y271 20/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5268521 1.00 CYSLTR2 (0.73) CYSLTR2CYSLTR1
SCHEMBL5268527 1.00 CYSLTR2 (0.73) CYSLTR2CYSLTR1
SCHEMBL3561782 0.94 CYSLTR2 (0.72) CYSLTR2CYSLTR1
SCHEMBL3561779 0.94 CYSLTR2 (0.72) CYSLTR2CYSLTR1
SCHEMBL3561775 0.94 CYSLTR2 (0.72) CYSLTR2CYSLTR1
SCHEMBL3563223 0.93 CYSLTR2 (0.70) CYSLTR2CYSLTR1
SCHEMBL3563220 0.93 CYSLTR2 (0.70) CYSLTR2CYSLTR1
SCHEMBL3563219 0.93 CYSLTR2 (0.70) CYSLTR2CYSLTR1
SCHEMBL3561076 0.93 CYSLTR2 (0.73) CYSLTR2CYSLTR1
SCHEMBL3561077 0.93 CYSLTR2 (0.73) CYSLTR2CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1852420-B1 Indole compounds for treating respiratory disorders ONO PHARMACEUTICAL CO (JP) 2012-10-17 EP disclosed
EP-1852420-A1 INDOLE COMPOUND AND USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2007-11-07 EP disclosed