Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 11/20 | 0.74 |
| ▸ | NR1H3 | Q13133 | 9/20 | 0.74 |
| ▸ | RXRA | P19793 | 9/20 | 0.67 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679291 | 0.87 | NR1H2 (0.78) | NR1H2NR1H3RXRAMAOBMAOA | |
| SCHEMBL1678331 | 0.85 | NR1H2 (1.00) | NR1H2NR1H3RXRAPPARGPPARD | |
| SCHEMBL5267508 | 0.85 | NR1H2 (0.71) | NR1H2NR1H3RXRAMAOBMAOA | |
| SCHEMBL1678610 | 0.84 | NR1H2 (0.72) | NR1H2NR1H3RXRAMAOBMAOA | |
| SCHEMBL1679248 | 0.84 | NR1H2 (0.82) | NR1H2NR1H3RXRAPPARGPPARD | |
| SCHEMBL1678699 | 0.84 | NR1H2 (0.72) | NR1H2NR1H3RXRAMAOBMAOA | |
| SCHEMBL1678988 | 0.84 | NR1H2 (0.82) | NR1H2NR1H3RXRAPTGER4SRD5A2 | |
| SCHEMBL1679093 | 0.84 | NR1H2 (0.82) | NR1H2NR1H3RXRAMAOBMAOA | |
| SCHEMBL1678343 | 0.84 | NR1H2 (0.72) | NR1H2NR1H3RXRAPTGER4ADAMTS4 | |
| SCHEMBL1679684 | 0.84 | NR1H2 (0.72) | NR1H2NR1H3RXRAMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806332-A1 | BENZENE COMPOUND HAVING 2 OR MORE SUBSTITUENTS | Daiichi Sankyo Company, Limited (JP) | 2007-07-11 | — | — | EP | disclosed |