SCHEMBL5268844

SCHEMBL5268844

O=C(NN1CC2CCCC2C1)C1=NN(c2ccc(Cl)cc2Cl)[C@H](c2ccc(F)cc2)C1

nearest known ligand 0.67

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 19/20 0.67
CNR2 P34972 11/20 0.67
NR3C2 P08235 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14621869 1.00 CNR1 (0.67) CNR1CNR2NR3C2
SCHEMBL2019407 1.00 CNR1 (0.67) CNR1CNR2NR3C2
SCHEMBL5271465 1.00 CNR1 (0.67) CNR1CNR2NR3C2
Hydrochloric Acid SCHEMBL2017124 0.99 CNR1 (0.66) CNR1CNR2NR3C2
SCHEMBL2018661 0.94 CNR1 (0.74) CNR1CNR2
SCHEMBL4605624 0.94 CNR1 (0.74) CNR1CNR2
SCHEMBL2018426 0.94 CNR1 (0.74) CNR1CNR2
Hydrochloric Acid SCHEMBL2017005 0.94 CNR1 (0.73) CNR1CNR2
Hydrochloric Acid SCHEMBL2019203 0.94 CNR1 (0.73) CNR1CNR2
SCHEMBL5270166 0.92 CNR1 (0.68) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1849783-A1 Octahydropentalene-substituted pyrazoline compounds, their preparation and use as medicaments LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2007-10-31 EP disclosed