⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15043693 | 1.00 | LIPA (0.38) | — | |
| SCHEMBL14576723 | 1.00 | LIPA (0.38) | — | |
| SCHEMBL15043694 | 0.92 | KMT2A (0.40) | — | |
| SCHEMBL10174290 | 0.89 | NAMPT (0.36) | — | |
| SCHEMBL15445405 | 0.89 | ANPEP (0.47) | — | |
| SCHEMBL12424289 | 0.89 | ESR1 (0.33) | — | |
| SCHEMBL15067035 | 0.89 | EPHX2 (0.36) | — | |
| SCHEMBL156237 | 0.88 | — | — | |
| SCHEMBL1396131 | 0.88 | — | — | |
| SCHEMBL23168695 | 0.87 | PLG (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 314 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140051854-A1 | PROCESS FOR THE PREPARATION OF KEY INTERMEDIATES FOR THE SYNTHESIS OF STATINS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | LEK PHARMACEUTICALS D.D. (SI) | 2014-02-20 | — | — | US | claimed |
| EP-2598484-A1 | PROCESS FOR THE PREPARATION OF KEY INTERMEDIATES FOR THE SYNTHESIS OF STATINS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | LEK Pharmaceuticals d.d. (SI) | 2013-06-05 | — | — | EP | claimed |
| CN-103119022-A | Process for the preparation of key intermediates for the synthesis of statins or pharmaceutically acceptable salts thereof | LEK PHARMACEUTICALS | 2013-05-22 | — | — | CN | claimed |
| EP-2423195-A1 | Process for the preparation of key intermediates for the synthesis of statins or pharmaceutically acceptable salts thereof | LEK Pharmaceuticals d.d. (SI) | 2012-02-29 | — | — | EP | claimed |
| WO-2012013325-A1 | PROCESS FOR THE PREPARATION OF KEY INTERMEDIATES FOR THE SYNTHESIS OF STATINS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | LEK PHARMACEUTICALS D.D. (SI) | 2012-02-02 | — | — | WO | claimed |
| US-20250326769-A1 | HETEROAROMATIC MACROCYCLIC ETHER CHEMOTHERAPEUTIC AGENTS | NUVALENT INC (US) | 2025-10-23 | — | — | US | disclosed |
| EP-4605397-A1 | HETEROAROMATIC MACROCYCLIC ETHER CHEMOTHERAPEUTIC AGENTS | Nuvalent, Inc. (US) | 2025-08-27 | — | — | EP | disclosed |
| US-12358887-B2 | IKAROS Zinc Finger Family degraders and uses thereof | GILEAD SCIENCES, INC. (US) | 2025-07-15 | — | — | US | disclosed |
| WO-2025035759-A1 | KIF18A INHIBITOR AND USE THEREOF | 深圳市祥根生物有限公司 | 2025-02-20 | — | — | WO | disclosed |
| EP-4464703-A2 | IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF | Gilead Sciences, Inc. (US) | 2024-11-20 | — | — | EP | disclosed |
| EP-4245756-B1 | IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF | GILEAD SCIENCES INC (US) | 2024-10-09 | — | — | EP | disclosed |
| CN-118725980-A | Refining method of coffee essential oil | 杭州佳嘉乐生物技术有限公司 | 2024-10-01 | — | — | CN | disclosed |
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |
| US-4960779-A | Pyrrole derivatives, and pharmaceutical compositions which contain them and pharmacological methods of use | RHONE-POULENC SANTE (FR) | 1990-10-02 | — | — | US | disclosed |
| EP-0351649-A2 | 2,2-Dihalocyclopropyl-hydroxy-ethyl triazoles | BAYER AG (DE) | 1990-01-24 | — | — | EP | disclosed |
| EP-0351647-A2 | 2,2-Difluorocyclopropyl derivates | BAYER AG (DE) | 1990-01-24 | — | — | EP | disclosed |
| EP-0080102-A1 | Cycloalkyl-(alpha-triazolyl-beta-hydroxy) ketones, process for their preparation and their use as fungicides and plant growth regulators | BAYER AG (DE) | 1983-06-01 | — | — | EP | disclosed |
| EP-0002850-B1 | NOVEL INTERMEDIATES IN THE PREPARATION OF CYCLOPROPYLCARBOXYLATE ESTERS AND PROCESS FOR THEIR MANUFACTURE | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1982-02-17 | — | — | EP | disclosed |
| US-4247711-A | CHEMICAL INTERMEDIATES FOR PYRETHRUM PESTICIDES | SHELL OIL COMPANY (US) | 1981-01-27 | — | — | US | disclosed |
| US-4093622-A | Pyridine esters of cyclopropane-carboxylic acid | ZOECON CORPORATION (US) | 1978-06-06 | — | — | US | disclosed |