SCHEMBL5269987

SCHEMBL5269987

CCc1cc(Cl)ccc1O.Cc1cc(Cl)ccc1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 3/20 0.57
MEN1 O00255 2/20 0.57
CYP3A4 P08684 2/20 0.57
HPGD P15428 2/20 0.57
ALOX15 P16050 2/20 0.57
KMT2A Q03164 2/20 0.57
HSP90AA1 P07900 2/20 0.57
SLC22A1 O15245 1/20 0.57
USP2 O75604 1/20 0.57
LMNA P02545 1/20 0.57
MAPT P10636 1/20 0.57
HSPD1 P10809 1/20 0.57
HSPA5 P11021 1/20 0.57
IDO1 P14902 1/20 0.57
ALOX12 P18054 1/20 0.57
CASP1 P29466 1/20 0.57
HTT P42858 1/20 0.57
BLM P54132 1/20 0.57
HSPE1 P61604 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7858971 0.92 MEN1 (0.49) HIF1AMEN1CYP3A4HPGDALOX15
SCHEMBL364080 0.90 HIF1A (0.68) HIF1AMEN1CYP3A4HPGDALOX15
Parachlorophenol SCHEMBL7607526 0.87 ESR2 (0.44) HIF1AMEN1CYP3A4HPGDALOX15
Benzene SCHEMBL574407 0.86 HIF1A (0.63) HIF1AMEN1CYP3A4HPGDALOX15
SCHEMBL171059 0.84
SCHEMBL5187389 0.83 HIF1A (0.50) HIF1AMEN1CYP3A4HPGDALOX15
SCHEMBL28261421 0.82 ESR2 (0.59) HIF1AMEN1CYP3A4HPGDALOX15
Potassium SCHEMBL30562954 0.82 ESR2 (0.59) HIF1AMEN1CYP3A4HPGDALOX15
SCHEMBL30991479 0.82 ESR2 (0.59) HIF1AMEN1CYP3A4HPGDALOX15
SCHEMBL27457915 0.82 ESR2 (0.59) HIF1AMEN1CYP3A4HPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1755381-A2 ANTIMICROBIAL SILICON OXIDE FLAKES CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) 2007-02-28 EP claimed
WO-2005107456-A2 ANTIMICROBIAL SILICON OXIDE FLAKES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-11-17 WO claimed
EP-1755381-A2 ANTIMICROBIAL SILICON OXIDE FLAKES CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) 2007-02-28 EP disclosed
WO-2005107456-A2 ANTIMICROBIAL SILICON OXIDE FLAKES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-11-17 WO disclosed
US-20050233930-A1 Disinfectant cleaning compositions RECKITT BENCKISER INC. (US) 2005-10-20 US disclosed