SCHEMBL5272178

SCHEMBL5272178

O=C(O)C(Cc1ccc(O)cc1)Oc1ccc(C(F)(F)F)cc1

nearest known ligand 0.80

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.80
PPARA Q07869 18/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5609291 0.86 PPARG (0.59) PPARGPPARA
SCHEMBL5609279 0.86 PPARG (0.59) PPARGPPARA
SCHEMBL4168487 0.84 PPARG (0.57) PPARGPPARA
SCHEMBL5609118 0.84 PPARG (0.78) PPARGPPARA
SCHEMBL5609132 0.84 PPARG (0.78) PPARGPPARA
SCHEMBL6556100 0.82 PPARG (0.73) PPARGPPARA
SCHEMBL5610143 0.81 PPARG (0.76) PPARGPPARA
SCHEMBL5610135 0.81 PPARG (0.76) PPARGPPARA
SCHEMBL6713091 0.79 PPARG (0.64) PPARGPPARA
SCHEMBL6713093 0.79 PPARG (0.64) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1844015-A2 NOVEL HETEROCYCLIC OXIME DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME Les Laboratoires Servier (FR) 2007-10-17 EP disclosed
WO-2006079719-A2 NOVEL HETEROCYCLIC OXIME DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME LES LABORATOIRES SERVIER (FR) 2006-08-03 WO disclosed