Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14590112 | 0.89 | TSHR (0.59) | SLC5A2TSHRPTPN1LMNAKMT2A | |
| SCHEMBL5271015 | 0.85 | TSHR (0.70) | SLC5A2TSHRPTPN1LMNAKMT2A | |
| SCHEMBL12731192 | 0.85 | TSHR (0.76) | SLC5A2TSHRPTPN1LMNAKMT2A | |
| SCHEMBL5523365 | 0.80 | TSHR (0.73) | TSHRPTPN1LMNAKMT2ACA12 | |
| SCHEMBL12509908 | 0.80 | TSHR (0.73) | TSHRPTPN1LMNAKMT2ACA12 | |
| SCHEMBL14590100 | 0.78 | PTPN1 (0.49) | SLC5A2TSHRPTPN1LMNAKMT2A | |
| SCHEMBL5275185 | 0.78 | TSHR (0.48) | SLC5A2TSHRPTPN1LMNAKMT2A | |
| SCHEMBL18427873 | 0.78 | TSHR (0.65) | TSHRPTPN1LMNAKMT2ACA12 | |
| SCHEMBL12725076 | 0.78 | TSHR (0.65) | SLC5A2TSHRPTPN1LMNAKMT2A | |
| SCHEMBL12510088 | 0.78 | TSHR (0.70) | TSHRPTPN1LMNAKMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169761-B2 | Azulene derivatives and salts thereof | ASTELLAS PHARMA INC. (JP) | 2007-01-30 | — | — | US | disclosed |
| US-7169761-B2 | Azulene derivatives and salts thereof | ASTELLAS PHARMA INC. (JP) | 2007-01-30 | — | — | US | disclosed |
| US-7169761-B2 | Azulene derivatives and salts thereof | ASTELLAS PHARMA INC. (JP) | 2007-01-30 | — | — | US | disclosed |
| EP-1553094-A1 | AZULENE DERIVATIVES AND SALTS THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2005-07-13 | — | — | EP | disclosed |
| US-20050124555-A1 | Azulene derivatives and salts thereof | ASTELLAS PHARMA INC. (JP) | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124555-A1 | Azulene derivatives and salts thereof | SLC5A1, SLC5A2, SLC2A1 | SLC5A2 2/4885TSHR 1442/4885PTPN1 150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.